Allergy testing in children: at what age and which test is useful
October 21, 2026about 15 minutesby mybody®x Editorial & Expert Team

The key points
In infants and toddlers, specific IgE, or allergy antibodies against individual triggers, is often measured in the blood instead of performing a skin test (Worm et al., 2021). Testing is prompted by a well-founded suspicion, discussed with the pediatrician's office: the guideline does not recommend broad screening without suspicion of a food allergy (Worm et al., 2021). An IgE level indicates sensitization, not a diagnosis.
In general, a skin test is usually performed first after talking with a doctor (IQWiG, 2024), while the guideline instead prefers measuring IgE in the blood for children (Worm et al., 2021).
Positive specific IgE only becomes significant when accompanied by a clearly matching patient history or a positive challenge test (Worm et al., 2021).
IgE can also be elevated in people without allergies, for example in people who smoke (IQWiG, 2024).
An overview of allergy tests for children
| Test | What it shows | In children |
|---|---|---|
| Prick test | Sensitization; it is the most important skin test for an immediate-type allergy (Allergieinformationsdienst, 2023) | Usually the first test after talking with a doctor (IQWiG, 2024) |
| Blood test for specific IgE | Sensitization, which IQWiG (2024) describes as an indication, not proof | Often used instead of a skin test in infants and toddlers (Worm et al., 2021) |
| Challenge test | Makes sensitization significant when considered alongside the patient's history (Worm et al., 2021) | Only when the skin or blood test does not provide a clear result (IQWiG, 2024) |
In this article
At what age can children have an allergy test?
Sensitization can be tested even in infants and toddlers: according to the guideline, specific IgE is often measured in their blood instead of performing a skin test (Worm et al., 2021). The reason for testing is what matters: symptoms and a well-founded suspicion.
Key takeaway
In children, sensitization is preferably tested for by measuring IgE in the blood, while adults are often tested using a skin test (Worm et al., 2021).
To clarify the terms: IgE stands for immunoglobulin E, or class E antibodies. The immune system produces them against certain proteins, such as those in food, and upon renewed contact they mediate the allergic reaction (Allergy Information Service, 2023). When these specific IgE antibodies are present, this is called allergic sensitization (Environmental Medicine Commission at the Robert Koch Institute, 2016).
Anyone who thinks young children cannot be tested will find the opposite in two sources. The guidelines on IgE-mediated food allergies explicitly list blood IgE testing as an alternative to skin testing for infants and toddlers (Worm et al., 2021). The Allergy Information Service (2023) says that doctors perform a blood test on younger children, as well as when a skin test cannot be performed.
For parents, another point is even more important, because a positive result can quickly sound like a diagnosis: an IgE level indicates sensitization, not a diagnosis. The Environmental Medicine Commission at the RKI (2016) describes sensitization as a prerequisite for an allergy, which can also be present without symptoms.
The Institute for Quality and Efficiency in Health Care (IQWiG, 2024) describes the blood test as an indication of an allergy, not proof of one. A positive result is significant only when considered alongside a clearly matching medical history or a positive provocation test (Worm et al., 2021). Our article explains what an allergy is in general: What is an allergy?
What allergy tests are available for children?
IQWiG (2024) describes three types of allergy tests, used one after another in a stepwise process. The guidelines place a particular emphasis on blood tests for children (Worm et al., 2021).
According to IQWiG (2024), the process follows this order after talking with the doctor:
- Skin test, such as the prick test: This is usually done first (IQWiG, 2024).
- Blood test: It is used when a skin test is difficult or too risky (IQWiG, 2024). According to IQWiG (2024), some allergens are also unavailable as ready-made solutions for skin testing.
- Provocation test: It only makes sense once skin or blood tests have failed to show clear results (IQWiG, 2024).
IQWiG (2024) describes these steps in general. The guidelines add what is given different weight in children, shifting the focus to measuring specific IgE in the blood (Worm et al., 2021). These accounts do not contradict each other. They describe the same approach from two perspectives: one for everyone and one focused on children.
A separate article covers the cost and process of an allergy test. This article focuses on children, and on which test is right at what age.
Not every reaction to a food is an allergy. Skin and blood tests look for IgE sensitization. The article on the difference between allergy and intolerance explains how these differ.
Cited source
“Sensitization is a prerequisite for an allergy, i.e. the occurrence of allergic symptoms; however, it can also be present without symptoms occurring upon contact with the allergen (‘clinically silent sensitization’).”
Environmental Medicine Commission at the Robert Koch Institute
Position paper, Allergo Journal International, 2016
This sentence explains why a test result alone is not enough. Skin and blood tests show whether sensitization is present. On their own, they cannot tell you whether it causes symptoms.
Blood test or prick test: Which allergy test is right for children?
According to the Allergieinformationsdienst (2023), a doctor performs a blood test in younger children. In general, after talking with the doctor, the skin test is usually done first (IQWiG, 2024). Both show sensitization; neither alone shows an allergy.

You don’t decide between the two tests alone. The decision is made at the doctor’s office after discussing what you’ve observed. Factors include whether a skin test would be difficult or too risky for the child, and whether the allergen being tested for is available as a ready-made solution for the skin test (IQWiG, 2024).
Prick testing in children
Best for: the first step after talking to the doctor
✓ What is being tested: The prick test provides evidence of an immediate-type allergy and shows increased allergic susceptibility, or sensitization, for example to allergens in the air or in food (Allergieinformationsdienst, 2019).
✓ When used in children: It is considered the most important skin test for an immediate-type allergy (Allergy Information Service, 2023). If a skin test cannot be performed or the child is still very young, a blood test is done instead (Allergy Information Service, 2023).
✕ What it doesn’t show: Whether sensitization causes symptoms, because it can be associated with symptoms, but doesn’t have to be (Allergy Information Service, 2023).
Verdict: Generally the usual first test (IQWiG, 2024), but not the approach preferred by the guideline for children (Worm et al., 2021).
Blood test for specific IgE in children
Best for: infants and toddlers
✓ What is tested: The amount of IgE antibodies in the blood sample is measured in a laboratory, and it may be elevated in the case of an allergy (IQWiG, 2024).
✓ When used in children: Often instead of a skin test in infants and toddlers (Worm et al., 2021). Also when a skin test is difficult or too risky (IQWiG, 2024).
✕ What it doesn’t show: Proof of an allergy, because according to IQWiG (2024), the test only indicates a possible allergy.
Verdict: For children, this is the approach preferred by the guideline (Worm et al., 2021), with the same limitation as any IgE result.
For parents, what matters most afterward is how the result is interpreted. Both methods show sensitization, and the doctor assesses whether it fits the symptoms together with the patient’s history (Worm et al., 2021).
What does an IgE allergy test in children show, and what doesn’t it show?
An IgE test shows whether specific antibodies to a substance are present in the blood, meaning sensitization. As a rule of thumb, only half of sensitizations in the population are actually associated with symptoms (Worm et al., 2021).
An elevated result is therefore not automatically an allergy. According to IQWiG (2024), IgE antibodies can also be present in higher amounts in the blood without an allergy, for example in people who smoke or have a parasitic infection.
The level of the result also says little reliably about the severity of symptoms: the amount of allergy antibodies is not necessarily related to it (IQWiG, 2024). A high result therefore does not necessarily mean strong reactions.
If sensitization is present but there are no symptoms, it is called silent sensitization (Allergy Information Service, 2023). In a child without symptoms, a positive result may be just that: measurable, but without symptoms in everyday life.
For total IgE, the Allergieinformationsdienst (2019) gives a normal value of up to 100 IU/ml, or international units per milliliter of serum, for adults and children aged ten and older. Different values apply to children under ten, depending on their age (Allergieinformationsdienst, 2019). The information on your child's test report is what matters.
The article explains how these antibodies are produced in the first place: how an allergy develops.
The key facts and figures
up to 100 IU/ml
Normal value for total IgE from age ten; different values apply to younger children depending on age (Allergieinformationsdienst, 2019).
half
As a rule of thumb, only half of sensitizations in the population are associated with symptoms (Worm et al., 2021).
37,1 %
of 3- to 17-year-olds in Germany were sensitized to a mix of multiple allergens (Thamm et al., 2018).
16,1 %
of children and adolescents had at least one of three allergic diseases, more than one in six children (Thamm et al., 2018).
Source for each figure in parentheses; the KiGGS data are from 2014 to 2017 (Thamm et al., 2018).
Which allergies are common in children?
In the Robert Koch Institute's KiGGS study, more than one in six children (16.1%) had at least one of three allergic diseases; hay fever was the most common (Thamm et al., 2018).
KiGGS is a cross-sectional study by the Robert Koch Institute involving children and adolescents in Germany (Thamm et al., 2018). The figures from the second wave are from 2014 to 2017 and indicate what percentage of 0- to 17-year-olds were affected in the past twelve months (Thamm et al., 2018).
The three conditions examined, each as a percentage of cases in the past twelve months:
- Hay fever: 8.8% (Thamm et al., 2018)
- Atopic dermatitis: 7.0% (Thamm et al., 2018)
- Bronchial asthma: 3.5% (Thamm et al., 2018)
These percentages have not changed significantly since the first KiGGS survey, which the authors interpret as stabilization at a high level (Thamm et al., 2018).
In addition, 37.1% of 3- to 17-year-olds were sensitized to a mix of multiple allergens (Thamm et al., 2018). The two percentages refer to different age groups and cannot be subtracted from each other. They only give a rough indication that sensitization is more widespread than allergic diseases (Thamm et al., 2018).
For food allergies, the guideline names these foods as the most common triggers in children and adolescents (Worm et al., 2021):
- Milk
- Chicken egg
- Soy
- Wheat
- Peanut
- Tree nuts
A 2004 study shows how common confirmed food allergies are: it found a food allergy confirmed by a challenge test in 4.2% of the children studied (Worm et al., 2021).
Not all allergies follow the same course. According to the guideline, peanut and tree nut allergies can persist into adulthood (Worm et al., 2021). The article Nut allergy or nut intolerance explains whether a reaction to nuts is an allergy or an intolerance.
When should a child be tested for allergies?
A test is useful if your child has symptoms and there is a justified suspicion that you discuss with your child’s pediatrician. The guideline advises against a broad screening test without a justified suspicion of a food allergy (Worm et al., 2021).
The reason for concern can look very different in everyday life. One child gets a rash after eating. Another sneezes every spring, or coughs as soon as they play with the cat at their grandparents’ house. These observations are the starting point, not the test.
In practice, the process begins with a conversation with the doctor, followed usually by the first test (IQWiG, 2024). For this conversation, it helps to note your observations: what your child ate or touched and what happened afterward.
Why not test just in case? Positive specific IgE only becomes significant when combined with a clearly matching medical history or a positive challenge test (Worm et al., 2021). Without symptoms, a result lacks precisely this medical history. Sensitization can also be present without symptoms occurring on contact with the allergen (Commission on Environmental Medicine at the RKI, 2016).
A test is useful if …
your child develops symptoms after contact with a suspected trigger (IQWiG, 2024).
there is a justified suspicion that fits the medical history (Worm et al., 2021).
you coordinate the process with your child’s pediatrician, who will choose the appropriate test.
A test is of little use if …
it is intended as a screening test without a justified suspicion (Worm et al., 2021).
there is just one result without symptoms, since sensitization can also be silent (Commission on Environmental Medicine at the RKI, 2016).
The AllergoCheck: What a home blood test can show
The mybody®x AllergoCheck (MYBODY Lab GmbH) measures IgE against 54 allergens in capillary blood, providing an indication of sensitization. It does not provide a diagnosis and is not intended as a screening test for people without symptoms.
The sample is collected at home: a finger prick is all that’s needed, and the tube is returned in the enclosed return bag. The sample is analyzed at a specialist laboratory in Germany, and the report is available as a PDF in the customer portal.
IgE is measured against 54 allergens, including those from pollen and foods. Cat and dog allergens are also included. A positive result for cat indicates sensitization, but not whether the coughing at the grandparents’ house is caused by it.
AllergoCheck is approved for ages 6 and up. This is the product’s age approval, not an age limit for allergy testing: for younger children, consult a pediatrician.
An elevated IgE level indicates sensitization, not necessarily symptoms. Some people have measurable antibodies but never react. Whether this develops into an allergy depends on the symptoms, and that is a matter for a doctor.
This test is intended for people with symptoms, not as a preventive screening test. Its purpose is to help you prepare for a conversation with your pediatrician: it provides an indication of sensitization that you can take with you. It does not replace that conversation, and the doctor decides whether to follow up with a skin test or a challenge test.
From the mybody®x range · Blood test
AllergoCheck | Food and allergy test
Measures IgE against 54 allergens in capillary blood, including cat and dog, as an indication of sensitization. It does not provide a diagnosis and is not intended as a screening test for people without symptoms. The result helps you prepare for a conversation with your pediatrician.
approved for ages 6 and up
Lab analysis 3–5 business days after sample receipt
What are the limitations of allergy testing for children?
Skin and blood tests show sensitization, not a diagnosis, and the same applies to AllergoCheck. The sources for this guide also have limitations you should know about.
- The definition of sensitization comes from a position paper, not a study with original data (Kommission Umweltmedizin am RKI, 2016).
- IQWiG (2024) describes medical testing in which the blood sample is taken from a vein in the arm. AllergoCheck uses capillary blood from the finger.
- The guideline is from 2021 (Worm et al., 2021). The 4.2% rate of confirmed food allergies in children comes from a single study conducted in 2004 (Worm et al., 2021).
- Two pages from the Allergieinformationsdienst, one on skin tests and one on laboratory tests, are from 2019 (Allergieinformationsdienst, 2019).
- The KiGGS figures come from the summary of the study using data from 2014 to 2017 (Thamm et al., 2018). The rates of disease and sensitization refer to different age groups.
- AllergoCheck shows sensitization, not a diagnosis. Whether an allergy is present is determined by the symptoms and a conversation at the doctor’s office.
What should parents remember about allergy testing for children?
It doesn’t start with the test, but with what you observe in your child. You take these observations to the pediatrician’s office, where they choose between a skin test and a blood test; according to the guideline, for the youngest children the choice tends to be the blood test (Worm et al., 2021). A positive result indicates sensitization; it becomes significant only when there is a clearly matching medical history or a positive challenge test (Worm et al., 2021). Knowing this makes it easier to interpret any result calmly.
Frequently asked questions
Do children outgrow a milk allergy?
The outlook is good for an early milk protein allergy: the guideline describes a good prognosis for developing tolerance spontaneously, meaning that the child will tolerate the food over time (Worm et al., 2021). The outlook is different for peanut and tree nut allergies, which can persist into adulthood (Worm et al., 2021). Your child’s pediatrician will assess how it develops over time.
What does a total IgE level over 100 mean?
For adults and children aged ten and older, the normal total IgE level is up to 100 IU/ml (Allergieinformationsdienst, 2019). Different age-dependent values apply to younger children (Allergieinformationsdienst, 2019). A higher level is not proof of an allergy, because according to IQWiG (2024), there can also be more IgE antibodies in the blood without an allergy, for example due to a parasitic infection. The doctor’s office interprets what the level means alongside the symptoms.
What is silent sensitization?
Silent sensitization refers to sensitization without symptoms (Allergieinformationsdienst, 2023). The RKI Commission on Environmental Medicine (2016) describes it as sensitization that is present without symptoms occurring on contact with the allergen. A rule of thumb shows how common this is: Only half of sensitizations in the population are actually associated with symptoms (Worm et al., 2021).
How many children have a food allergy?
A 2004 study found a food allergy confirmed by a challenge test in 4.2% of the children studied; the figure for adults was 3.7% (Worm et al., 2021). A different figure applies to the population as a whole: surveys show that around 30 percent of people say they suffer from a food allergy, but verifiable reactions are much less common (Allergieinformationsdienst, 2023). The 4.2% comes from a single study and should be interpreted only in that context (Worm et al., 2021).
When is a challenge test necessary?
According to IQWiG (2024), a challenge test is only useful if a skin test or blood test has not produced clear results. It is therefore the final step in the staged procedure. The guideline describes its significance as follows: Positive specific IgE only becomes meaningful when accompanied by a clearly matching medical history or a positive challenge test (Worm et al., 2021). The doctor decides whether your child should have such a test.
Next step
With an indication to take to the pediatrician
If there are symptoms and a suspicion, AllergoCheck shows whether IgE against 54 allergens can be detected. The result indicates sensitization, which you can discuss with your healthcare provider.
Go to AllergoCheck How much an allergy test costs and what to expect An overview of costs and procedureRead more
Sources
- Environmental Medicine Commission at the Robert Koch Institute: Current status of the prevalence of allergies in Germany, Allergo Journal International (as of 2016) – rki.de; IQWiG: What allergy tests are available? (as of 2024) – gesundheitsinformation.de
- Worm M. et al.: Update of the S2k guideline on IgE-mediated food allergies, Allergologie select (as of 2021) – europepmc.org
- Allergy Information Service (Helmholtz Munich): Food allergies and allergy diagnosis (as of 2019 and 2023) – allergieinformationsdienst.de
- Thamm R. et al. (KiGGS Wave 2, Robert Koch Institute): Allergic diseases in children and adolescents in Germany, Journal of Health Monitoring (as of 2018) – europepmc.org
The statements on sensitization and silent sensitization are based on [1] and [3]. The stepwise approach and the limitations of the blood test follow IQWiG in [1]. The guideline in [2] recommends preferring blood tests for children. The triggers and course of food allergies also come from [2]. The figures for allergic diseases come from [4], and the normal value for total IgE comes from [3]. Product information for AllergoCheck is from mybody®x, information as of 20.10.2026.
mybody®x editorial and expert team
Allergies in children IgE and sensitization
This guide was created by the mybody®x editorial and expert team, based on the guidelines and professional information cited in the sources section. Learn more about the team on the authors page.
Published on 21.10.2026 · Last updated on 21.10.2026
The content is for general information and does not replace medical advice, diagnosis, or treatment. Reference ranges depend on the laboratory, method, and age; the information on your test results is always authoritative.
Our products are not intended to diagnose, treat, cure, or prevent diseases.
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